Paraneoplastic Syndrome Presenting with Polymyalgia Rheumatica-like Accumulations on ¹⁸F-fluorodeoxyglucose-Positron Emission Tomography/Computed Tomography

Abstract

A 70-year-old woman presented with a fever and pain in both lower extremities and the right shoulder and right upper arm continuously for approximately 3 months. ¹⁸F-fluorodeoxyglucose-positron emission tomography/computed tomography (¹⁸F-FDG/PET-CT) revealed the accumulation of FDG in the right shoulder, lumbar spinous processes, both ischial tuberosities, and both hips and greater trochanters, indicating polymyalgia rheumatica (PMR). In addition, upper gastrointestinal endoscopy revealed esophageal carcinoma. After endoscopic submucosal dissection was performed, her musculoskeletal symptoms spontaneously improved, and the ¹⁸F-FDG/PET-CT findings decreased. In light of these findings, she was diagnosed with paraneoplastic syndrome. When atypical features of PMR, such as asymmetric symptoms occur, we should search for malignancies.