Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
A Case Report of Painless Thyroiditis with TSH Receptor-blocking and Receptor-stimulating Autoantibodies
Keiichi Kamijo
キーワード: painless thyroiditis, M22-TRAb, TBAb, TSAb
ジャーナル オープンアクセス 早期公開

論文ID: 3212-19


We herein report a rare case of a 41-year-old woman with painless thyroiditis who was positive for TSH receptor-blocking (TBAbs) and receptor-stimulating autoantibodies (TSAbs) in the thyrotoxic phase. Her serum thyroid hormone levels were high, and TSH was undetectable. The low uptake of Tc-99m led to the diagnosis of painless thyroiditis. M22-TRAb, TBAb and TSAb were detectable in the thyrotoxic phase. Three months later, she became severely hypothyroid. M22-TRAb and TBAb were still strongly positive, although the TSAb levels had decreased to just above the reference range. In this case, TBAb led to hypothyroidism.

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