Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
Neurological Disorders Identified during Treatment of a SARS-CoV-2 Infection
Shinichi WadaYoji NagasakiYoko ArimizuMasatoshi ShimoYuta MatsukumaMasaki OkamotoShinichiro YoshidaIkkei OhashiGo HashimotoTakahiro KuwashiroMasahiro YasakaYasushi Okada
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JOURNALS OPEN ACCESS Advance online publication

Article ID: 5447-20


A 69-year-old man was admitted to our hospital under diagnosis of pneumonia due to SARS-CoV-2 (Day 0). He underwent endotracheal intubation from Day 3. Although his respiratory condition improved and anesthetic drugs were discontinued, no cough reflex was observed despite intubation having been performed until Day 17. His tendon reflexes were also diminished. We suspected that he had developed Guillain-Barré syndrome (GBS), and administered intravenous immunoglobulin from Day 18. The absence of cough reflex improved and extubation was successfully performed on Day 23. Neurological disorders including GBS should be considered when intubated SARS-CoV-2 patients present with a loss of cough reflex during the treatment period.

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