Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918

This article has now been updated. Please use the final version.

Myocarditis Following a COVID-19 Messenger RNA Vaccination: A Japanese Case Series
Yoshiki MurakamiMasaya ShinoharaYosuke OkaRyo WadaRyota NoikeHiroshi OharaTadashi FujinoTakanori Ikeda
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JOURNAL OPEN ACCESS Advance online publication

Article ID: 8731-21


COVID-19 vaccine-related myocarditis has been reported worldwide. We herein report two Japanese cases with suspected vaccine-related myocarditis. A 27-year-old man was admitted with chest pain 4 days after the second vaccination. An electrocardiogram (ECG) did not reveal any significant abnormalities. The second patient, a 37-year-old man, was admitted with chest pain 9 days after the first vaccination. His ECG exhibited ST-elevation in multiple leads. In both cases, cardiac magnetic resonance imaging findings were consistent with myocarditis. They recovered with symptomatic relief within a few days. These cases suggest that the benefit of COVID-19 vaccination exceeds the risk of vaccine-related myocarditis.

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© 2022 by The Japanese Society of Internal Medicine