Takotsubo-like Myocardial Dysfunction in a Patient with Botulism

Shuichi Tonomura; Yoshiaki Kakehi; Masatoshi Sato; Yuki Naito; Hisao Shimizu; Yasunobu Goto; Nobuyuki Takahashi

doi:10.2169/internalmedicine.8968-17

This article has now been updated. Please use the final version.

Takotsubo-like Myocardial Dysfunction in a Patient with Botulism

Shuichi Tonomura, Yoshiaki Kakehi, Masatoshi Sato, Yuki Naito, Hisao Shimizu, Yasunobu Goto, Nobuyuki Takahashi

Author information

Keywords: botulism, botulinum toxin A, Takotsubo syndrome, autonomic failure

JOURNAL OPEN ACCESS Advance online publication

Article ID: 8968-17

DOI https://doi.org/10.2169/internalmedicine.8968-17

The final version of this article is now available: Vol. 56 (2017), No. 21 pp. 2925-2927

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Abstract

Botulinum toxin A (BTXA) can disrupt the neuromuscular and autonomic functions. We herein report a case of autonomic system dysfunction that manifested as Takotsubo-like myocardial dysfunction in a patient with botulism. Takotsubo syndrome results in acute cardiac insufficiency, another fatal complication of botulism in addition to respiratory muscle paralysis, particularly in patients with cardiovascular disease.

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