Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918

This article has now been updated. Please use the final version.

Progressive Restrictive Ventilatory Impairment in Idiopathic Diffuse Pulmonary Ossification
Hidemasa MatsuoTomohiro HandaMichiko TsuchiyaTakeshi KuboAkihiko YoshizawaYuko NakayamaShuichi ShigaTakefumi HitomiSouichi AdachiHiroshi DateToyohiro HiraiSatoshi Ichiyama
Author information
JOURNAL OPEN ACCESS Advance online publication

Article ID: 9433-17

Details
Abstract

Diffuse pulmonary ossification (DPO) is a rare disease characterized by metaplastic bone formation in the lung. There are few reports with a long-term follow-up of this disease. We herein report a 47-year-old man diagnosed with idiopathic DPO at 30 years of age. The patient's vital capacity was normal until 36 years of age (3.39 L, 82.4% predicted), but it was severely decreased when he visited the hospital again at 47 years of age due to cough and dyspnea (1.98 L, 44.6% predicted). Chest computed tomography showed a significant increase in the number of high-density nodules, suggesting that the progression of DPO had caused restrictive ventilatory impairment.

Content from these authors
© 2018 by The Japanese Society of Internal Medicine
feedback
Top