Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
Charcot-Marie-Tooth Disease with Diaphragmatic Weakness
Shinobu OSANAIYuji AKIBAHitoshi NAKANOHiroyuki MATSUMOTOOsamu YAHARASokichi ONODERA
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1992 Volume 31 Issue 11 Pages 1267-1270

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Abstract

A 61-year-old man, who suffered from Charcot-Marie-Tooth disease (CMT) for 44 years, was evaluated for the respiratory disorder. He had diaphragmatic dysfunction induced by phrenic nerve disturbance. In this patient, central type apnea and hypopnea related to diaphragmatic weakness occurred during REM sleep, which induced accessory inspiratory muscle inhibition. Respiratory muscle dysfunction had not been generally recognized in CMT until recently, but its significance should be emphasized.
(Internal Medicine 31 : 1267-1270, 1992)

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© The Japanese Society of Internal Medicine
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