Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
Headache and Painful Lymphadenopathyin Extracranial or Systemic Infection: Etiology of NewDaily Persistant Headaches
Juan R. SANTONICarlos J. SANTONI-WILLIAMS
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1993 Volume 32 Issue 7 Pages 530-532

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Abstract

From 108 cases of new daily persistent headaches, clinical or laboratory evidence was found suggesting extracranial or systemic infections in: 28 cases (25.9%) of gastrointestinal mainly Salmonella, 28 (25.9%) urinary Coli, 16 (14.8%) Streptococcal, 4 (3.7%) each of Epstein Barr virus or Toxoplasma, and 1 (0.9%) each of Herpes Zoster or pneumonia. A group of 26 (24.1%) showed high Proteus OX titer or clinical adenoviral involvement. All had normal neurological examinations plus selective negative neuroimaging or spinal taps. The meanheadache duration was 13.8 days, and mean age 28.8 years. Prominent symptoms were fever in 37 (34.2%) cases, nausea/vomiting in 30 (27 %) and vertigo in 17 (15.7 % ). Diarrhea, dysuria, and abdominal discomfort were rare. Headache was a solitary symptomin 36 (33.3%). The predominant sign was painful cervical lymphadenopathy in 61 (56.5%). These cases represent 1.2% of our 9060 neurology patients.
(Internal Medicine 32: 530-532, 1993)

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