Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
Response to Octreotide of Intestinal Pseudoobstruction and Pneumatosis Cystoides Intestinalis Associated with Progressive Systemic Sclerosis
Toshiyuki KOBAYASHIMutsuhiro KobayashiMotoji NAKAKazuo NAKAJIMAAtsushi MOMOSEMakoto TOI
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1993 Volume 32 Issue 7 Pages 607-609

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Abstract

Intestinal pseudoobstruction and pneumatosis cystoides intestinalis are uncommon complications of progressive systemic sclerosis. We report a 26-year-old woman with this disorder who responded poorly to conventional treatment. Subcutaneous administration of octreotide, a longacting somatostatin analogue, at a dose of 50 μg/day for 3 weeks, relieved symptoms such as nausea and bloating. There was also a marked decrease of intestinal gas accumulation, as documented on X-ray films.
(Internal Medicine 32: 607-609, 1993)

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