Hypersensitivity Pneumonitis Induced by Inhalation of Mushroom (Pholiota nameko) Spores

Abstract

We describe the hyper sensitivity pneumonitis of a 49-year-old woman who had been cultivating the edible mushroom 'Pholiota nameko' for three years. Her clinical manifestations and laboratory findings including transbronchial lung biopsy (TBLB) and bronchoalveolar lavage fluid (BALF) were consistent with those of other forms of hypersensitivity pneumonitis. Counter-immunoelectrophoresis determined the causative antigen to be the spores of Pholiota nameko. The indoor cultivation method appeared to play a major role in the occurrence of the hypersensitivity pneumonitis.
(Internal Medicine 33: 683-685, 1994)