Chronic Hepatitis C Complicated by Coombs-Negative Hemolytic Anemia During Interferon Treatment

Noboru HIRASHIMA; Masashi MIZOKAMI; Etsuro ORITO; Manabu YAMAUCHI; Makoto NARITA; Makoto MIZUNO; Yasushi TOKUDA; Tatsunori NAKANO; Masaya KATO; Takuma MATSUMOTO; Kanji SUGIHARA; Katsushi KOYAMA; Atsuhiro YOSHIDA; Masataka OGINO

doi:10.2169/internalmedicine.33.300

Noboru HIRASHIMA, Masashi MIZOKAMI, Etsuro ORITO, Manabu YAMAUCHI, Makoto NARITA, Makoto MIZUNO, Yasushi TOKUDA, Tatsunori NAKANO, Masaya KATO, Takuma MATSUMOTO, Kanji SUGIHARA, Katsushi KOYAMA, Atsuhiro YOSHIDA, Masataka OGINO

Author information

Noboru HIRASHIMA
The Department of Gastroenterology, Nagoya Daini Red Cross Hospital
Masashi MIZOKAMI
The Second Department of Internal Medicine, Nagoya City University Medical School
Etsuro ORITO
The Second Department of Internal Medicine, Nagoya City University Medical School
Manabu YAMAUCHI
The Department of Gastroenterology, Nagoya Daini Red Cross Hospital
Makoto NARITA
The Department of Gastroenterology, Nagoya Daini Red Cross Hospital
Makoto MIZUNO
The Department of Gastroenterology, Nagoya Daini Red Cross Hospital
Yasushi TOKUDA
The Department of Gastroenterology, Nagoya Daini Red Cross Hospital
Tatsunori NAKANO
The Department of Gastroenterology, Nagoya Daini Red Cross Hospital
Masaya KATO
The Department of Gastroenterology, Nagoya Daini Red Cross Hospital
Takuma MATSUMOTO
The Department of Gastroenterology, Nagoya Daini Red Cross Hospital
Kanji SUGIHARA
The Department of Gastroenterology, Nagoya Daini Red Cross Hospital
Katsushi KOYAMA
The Department of Nephrology, Nagoya Daini Red Cross Hospital
Atsuhiro YOSHIDA
The Department of Nephrology, Nagoya Daini Red Cross Hospital
Masataka OGINO
The Department of Gastroenterology, Nagoya Daini Red Cross Hospital

Keywords: acute renal failure and hemolytic anemia

JOURNAL FREE ACCESS

1994 Volume 33 Issue 5 Pages 300-302

DOI https://doi.org/10.2169/internalmedicine.33.300

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Abstract

Autoimmune hemolytic anemia is an autoimmune diseases which is reported to be caused by interferon treatment. A 33-year-old male with chronic hepatitis C developed Coombs-negative hemolytic anemia, probably due to administration of interferon-α2b. This is, to our knowledge, the first report of chronic hepatitis C complicated by Coombs-negative hemolytic anemia during interferon treatment.
(Internal Medicine 33: 300-302, 1994)

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