Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
IgA Nephropathy Associated with Portal Hypertension in Liver Cirrhosis due to Non-Alcoholic and Non-A, Non-B, Non-C Hepatitis
Mono NAKAMURAAkira OHISHIReiko WATANABEKohtaro KANEKONoboru AOSAKITomohiko IIGAYATetsuo MONMAHitoshi SUGIURAYukari MIYOSHIKinichi HAMAGUCHI
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1994 Volume 33 Issue 8 Pages 488-491

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Abstract

A 69-year-old female was admitted to our hospital because of leg edema, proteinuria (2.1 g/day), and gross hematuria. She had non-alcoholic liver cirrhosis of unknown etiology. Esophageal varices also were found. Examination of the renal biopsy specimen revealed mesangial proliferative glomerulonephritis with IgA deposits. Propranolol was administered orally to reduce portal hypertension, resulting in a progressive decrease in urinary microalbumin excretion. This case suggests that portal hypertension is involved in the pathogenesis of IgA nephropathy in liver cirrhosis.
(Internal Medicine 33: 488-491, 1994)

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