Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
Central Diabetes Insipidus Caused by Pituitary Metastasis of Lung Cancer
Reikei MATSUDAEiko CHIBAIchiro KAWANAMinoru KIHARAMasakazu TOMIYAMAHikaru EBIRATadashi IKEGAMIHajime KITAMURA
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1995 年 34 巻 9 号 p. 913-918

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Tumor metastasis to the hypophyseal system has rarely been reported with either clinical or radiographic evidence. A 52-year-old woman presented with polydipsia, polyuria, and loss of appetite. She was diagnosed as having diabetes insipidus caused by pituitary micrometastasis of lung adenocarcinoma. After she had been treated with radiation therapy to the pituitary gland, the gland size was reduced as confirmed by magnetic resonance imaging, and her urine volume decreased. However, meningitis carcinomatosa appeared later. This was a rare case of secondary diabetes insipidus due to pituitary metastasis of lung cancer.
(Internal Medicine 34: 913-918, 1995)

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© The Japanese Society of Internal Medicine
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