Improvement of Hemolysis in Muscle Phosphofructokinase Deficiency by Restriction of Exercise

Hideki TOYODA; Tsutomu NAKASE; Makoto TOMEOKU; Koichi MORITA; Masami KATO; Tetsuya MURATA; Akira ONO; Masamichi KUWAJIMA; Norio KONO

doi:10.2169/internalmedicine.35.222

Hideki TOYODA, Tsutomu NAKASE, Makoto TOMEOKU, Koichi MORITA, Masami KATO, Tetsuya MURATA, Akira ONO, Masamichi KUWAJIMA, Norio KONO

Author information

Hideki TOYODA
The Department of Gastroenterology, Aichi Cancer Center Hospital
Tsutomu NAKASE
The Departments of Internal Medicine, Suzuka General Hospital
Makoto TOMEOKU
The Departments of Internal Medicine, Suzuka General Hospital
Koichi MORITA
The Departments of Internal Medicine, Suzuka General Hospital
Masami KATO
The Departments of Internal Medicine, Suzuka General Hospital
Tetsuya MURATA
The Departments of Pathology, Suzuka General Hospital
Akira ONO
The Second Department of Internal Medicine, Osaka University Medical School
Masamichi KUWAJIMA
The Second Department of Internal Medicine, Osaka University Medical School
Norio KONO
The School of Allied Health Sciences, Faculty of Medicine, Osaka University

Keywords: erythrocyte, glycogenosis type VII

JOURNAL FREE ACCESS

1996 Volume 35 Issue 3 Pages 222-226

DOI https://doi.org/10.2169/internalmedicine.35.222

Details

Abstract

A 29-year-old woman with muscle phosphofructokinase (PFK) deficiency had exercise intolerance, painful cramps, elevation of muscle enzyme levels in the serum and compensated hemolysis. After the restriction of exercise, the creatine kinase level and indirect bilirubin level decreased, and the reticulocyte count and haptoglobin level were normalized. It is suggested that the hemolysis which was accelerated by exercise was improved by restriction of exercise.
(Internal Medicine 35: 222-226, 1996)

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