Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
Varicella Pneumonia in a Healthy Adult Presenting with Severe Respiratory Failure
Toshihiro SHIRAIKoji SANOSatoru MATSUYAMAYumiko HONJOMisako TAKASHIMAYuzo SASADAShigekazu TAKAYANAGIKiyoaki NAGAMATSUMitsumasa NAWANOMisao FUSHIMIShiro IMOKAWAAtsuhiko SATO
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1996 Volume 35 Issue 4 Pages 315-318

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Abstract

We describe a case of varicella pneumonia in a 24-year-old healthy man presenting with severe respiratory failure. A chest radiograph showed diffuse, bilateral airspace consolidation; additional complications included liver dysfunction and thrombocytopenia. However, treatment with intravenous acyclovir and γ-globulin improved his clinical symptoms and signs. A greater than four-fold change in paired titers of the varicella-zoster virus antibody was observed. Bronchoalveolar lavage performed during the recovery phase revealed increased total cell and lymphocyte counts and a decreased CD4:CD8 ratio of T lymphocytes. Transbronchial lung biopsy findings were compatible with a diagnosis of interstitial pneumonia.
(Internal Medicine 35: 315-318, 1996)

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© The Japanese Society of Internal Medicine
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