Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
Takayasu's Arteritis Associated with Ulcerative Colitis; Genetic Factors in this Association
Yoshitaka MORITAMasahiro YAMAMURAKinichiro SUWAKIAtsushi MIMATsutomu ISHIZUMamoru HIROHATANaoki KASHIHARAHirofumi MAKINGZensuke OTA
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1996 Volume 35 Issue 7 Pages 574-578

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Abstract

Both ulcerative colitis and Takayasu's arteritis are thought to be organ-specific immunemediated inflammatory diseases. We present the rare case of a 23-year-old woman with a 4-year history of ulcerative colitis who developed Takayasu's arteritis one month after giving birth. She was found to carry the human leukocyte antigens (HLA)-B52 and DR2, which were previously noted to be associated with these inflammatory conditions in the Japanese population. The pathogenic relevance of this haplotype to the concomitant development of these two conditions is discussed.
(Internal Medicine 35: 574-578, 1996)

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