Sclerosing Cholangitis Associated with Hypereosinophilic Syndrome

Naomi ICHIKAWA; Atsuo TANIGUCHI; Hideto AKAMA; Hisataka ISHIGURO; Takeshi KURIHARA; Chihiro TERAI; Masako KARA; Sadao KASHIWAZAKI

doi:10.2169/internalmedicine.36.561

Naomi ICHIKAWA, Atsuo TANIGUCHI, Hideto AKAMA, Hisataka ISHIGURO, Takeshi KURIHARA, Chihiro TERAI, Masako KARA, Sadao KASHIWAZAKI

Author information

Naomi ICHIKAWA
The Department of Rheumatology, Institute of Rheumatology, Tokyo Women's Medical College
Atsuo TANIGUCHI
The Department of Rheumatology, Institute of Rheumatology, Tokyo Women's Medical College
Hideto AKAMA
The Department of Rheumatology, Institute of Rheumatology, Tokyo Women's Medical College
Hisataka ISHIGURO
The Aoyama Hospital, Tokyo Women's Medical College
Takeshi KURIHARA
The Aoyama Hospital, Tokyo Women's Medical College
Chihiro TERAI
The Department of Rheumatology, Institute of Rheumatology, Tokyo Women's Medical College
Masako KARA
The Department of Rheumatology, Institute of Rheumatology, Tokyo Women's Medical College
Sadao KASHIWAZAKI
The Department of Rheumatology, Institute of Rheumatology, Tokyo Women's Medical College

Keywords: eosinophilia, endoscopic retrograde cholangiopancreatography (ERCP), corticosteroid, ursodeoxycholic acid (UDCA)

JOURNAL FREE ACCESS

1997 Volume 36 Issue 8 Pages 561-564

DOI https://doi.org/10.2169/internalmedicine.36.561

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Abstract

A 15-year-old male with hypereosinophilic syndrome was admitted to our hospital because of general malaise and abnormal liver function tests. Endoscopic retrograde cholangiopancreatography demonstrated bile duct changes consistent with primary sclerosing cholangitis. The patient's liver profile tests returned to normal after treatment with prednisolone and ursodeoxycholic acid. In this case, eosinophils might have played an important role in the pathogenesis of the bile duct lesion.
(Internal Medicine 36: 561-564, 1997)

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