Unusual Accumulation of Glycogen in Liver Parenchymal Cells in a Patient with Anorexia Nervosa

Mina KOMUTA; Masaru HARADA; Takato UENO; Yasuyo UCHIMURA; Chizuko INADA; Keiichi MITSUYAMA; Shotaro SAKISAKA; Michio SATA; Kyuichi TANIKAWA

doi:10.2169/internalmedicine.37.678

Mina KOMUTA, Masaru HARADA, Takato UENO, Yasuyo UCHIMURA, Chizuko INADA, Keiichi MITSUYAMA, Shotaro SAKISAKA, Michio SATA, Kyuichi TANIKAWA

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Mina KOMUTA
The Second Department of Medicine, Kurume University School of Medicine
Masaru HARADA
The Second Department of Medicine, Kurume University School of Medicine
Takato UENO
The Second Department of Medicine, Kurume University School of Medicine
Yasuyo UCHIMURA
The Second Department of Medicine, Kurume University School of Medicine
Chizuko INADA
The Fourth Department of Medicine, Kurume University School of Medicine
Keiichi MITSUYAMA
The Second Department of Medicine, Kurume University School of Medicine
Shotaro SAKISAKA
The Second Department of Medicine, Kurume University School of Medicine
Michio SATA
The Second Department of Medicine, Kurume University School of Medicine
Kyuichi TANIKAWA
The Second Department of Medicine, Kurume University School of Medicine

Keywords: carbohydrate metabolism, electron microscopy, liver biopsy

JOURNAL FREE ACCESS

1998 Volume 37 Issue 8 Pages 678-682

DOI https://doi.org/10.2169/internalmedicine.37.678

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Abstract

Anorexia nervosa is an eating disorder characterized by a fear of weight gain and a preoccupation with body image. Although hepatic involvement has been reported in patients with anorexia nervosa, the mechanism is not fully understood. We describe a patient with anorexia nervosa with liver function abnormalities. Light and electron microscopic observations revealed a remarkable accumulation of glycogen in hepatocytes. These results suggest that adaptive responses to starvation may alter carbohydrate metabolism in patients with anorexia nervosa.
(Internal Medicine 37: 678-682, 1998)

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