Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
Two Similar Cases of Encephalopathy, Possibly a Reversible Posterior Leukoencephalopathy Syndrome: Serial Findings of Magnetic Resonance Imaging, SPECT and Angiography
Yasutaka TAJIMAKatsuyoshi ISONISHITakeshi KASHIWABAKunio TASHIRO
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1999 Volume 38 Issue 1 Pages 54-58

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Abstract

Two young women who had encephalopathy that resembled reversible posterior leukoencephalopathy syndrome are presented. The brain magnetic resonance imaging (MRI) of these patients exhibited similar T2-high signal lesions, mostly in the white matter of the posterior hemispheres. Xe-SPECT during the patients' symptomatic period showed hypoperfusion in the corresponding areas, and angiography demonstrated irregular narrowing of the posterior cerebral artery. Clinical manifestations subsided soon after treatment, and the abnormal radiological findings also were almost completely resolved. Thus, we concluded that transient hypoperfusion followed by ischemia and cytotoxic edema might have had a pivotal role in these cases.
(Internal Medicine 38: 54-58, 1999)

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