Rapidly Growing Primary Gastric B-Cell Lymphoma after Eradication of Helicobacter pylori

Norihiro FURUSYO; Kohki KANAMOTO; Shotaro NAKAMURA; Takashi YAO; Hiroshi SUEKANE; Yuji YANO; Iwao ARIYAMA; Jun HAYASHI; Seizaburo KASHIWAGI

doi:10.2169/internalmedicine.38.796

Rapidly Growing Primary Gastric B-Cell Lymphoma after Eradication of Helicobacter pylori

Norihiro FURUSYO, Kohki KANAMOTO, Shotaro NAKAMURA, Takashi YAO, Hiroshi SUEKANE, Yuji YANO, Iwao ARIYAMA, Jun HAYASHI, Seizaburo KASHIWAGI

Author information

Norihiro FURUSYO
The Department of General Medicine, Kyushu University Hospital
Kohki KANAMOTO
The Second Department of Internal Medicine, Kyushu University Hospital
Shotaro NAKAMURA
The Second Department of Internal Medicine, Kyushu University Hospital
Takashi YAO
The Second Department of Pathology, Kyushu University Hospital
Hiroshi SUEKANE
The Second Department of Internal Medicine, Kyushu University Hospital
Yuji YANO
The Second Department of Internal Medicine, Kyushu University Hospital
Iwao ARIYAMA
The Department of General Medicine, Kyushu University Hospital
Jun HAYASHI
The Department of General Medicine, Kyushu University Hospital
Seizaburo KASHIWAGI
The Department of General Medicine, Kyushu University Hospital

Keywords: mucosa-associated lymphoid tissue (MALT), low-grade lymphoma, high-grade lymphoma, MALT lymphoma

JOURNAL FREE ACCESS

1999 Volume 38 Issue 10 Pages 796-799

DOI https://doi.org/10.2169/internalmedicine.38.796

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Abstract

Helicobacter pylori (H. pylori) infection plays a decisive role in primary gastric B-cell lymphoma especially of mucosa-associated lymphoid tissue (MALT)-type. We treated a 47-year-old male patient with primary gastric B-cell lymphoma associated with H. pylori infection. Although antibiotic therapy for eradication of H. pylori caused great improvement in the low-grade MALT lymphoma-like lesion, the small areas of high-grade lesion rapidly formed a new bulky mass in only 8 weeks. This suggests that eradication of H. pylori is not effective for high-grade lymphoma.
(Internal Medicine 38: 796-799, 1999)

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