Aspergillus fumigatus Isolated from Blood Samples of a Patient with Pulmonary Aspergilloma after Embolization

Masafumi SEKI; Shigefumi MAESAKI; Kohji HASHIGUCHI; Yumiko TOMIYAMA; Kazunori TOMONO; Takayoshi TASHIRO; Shigeru KOHNO

doi:10.2169/internalmedicine.39.188

Aspergillus fumigatus Isolated from Blood Samples of a Patient with Pulmonary Aspergilloma after Embolization

Masafumi SEKI, Shigefumi MAESAKI, Kohji HASHIGUCHI, Yumiko TOMIYAMA, Kazunori TOMONO, Takayoshi TASHIRO, Shigeru KOHNO

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Keywords: blood culture, lysis centrifugation, galactomannan antigen, ELISA, itraconazole

JOURNAL FREE ACCESS

2000 Volume 39 Issue 2 Pages 188-190

DOI https://doi.org/10.2169/internalmedicine.39.188

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Abstract

Aspergillus DNA was detected by PCR in the serum sample of a 78-year-old man and galactomannan antigen of Aspergillus by sandwich ELISA was found. However, the infiltrative hyphae were not detected by the histopathologic examination of the lung. He developed hemoptysis, which required embolization of bronchial arteries. Aspergillus fumigatus was isolated from blood samples after embolization by the lysis centrifugation method. To our knowledge, this is probably the first case in which Aspergillus spp. has been isolated from the systemic circulatory blood in a patient with pulmonary aspergilloma after embolization.
(Internal Medicine 39: 188-190, 2000)

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