Successful Treatment of a Patient with Nephrotic Syndrome Associated with Chronic Lymphocytic Leukemia

Fumihiko TAKAHASHI; Yuji OGAWA; Naoyuki HASEBE; Syunsuke NATORI; Yoshihiko TOKUSASHI; Naoyuki MIYOKAWA; Kenjiro KIKUCHI

doi:10.2169/internalmedicine.39.256

Fumihiko TAKAHASHI, Yuji OGAWA, Naoyuki HASEBE, Syunsuke NATORI, Yoshihiko TOKUSASHI, Naoyuki MIYOKAWA, Kenjiro KIKUCHI

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Keywords: glomerulonephritis, malignancy, angiotensin-converting enzyme inhibitor

JOURNAL FREE ACCESS

2000 Volume 39 Issue 3 Pages 256-259

DOI https://doi.org/10.2169/internalmedicine.39.256

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Abstract

We report the case of a 62-year-old man with nephrotic syndrome associated with stage B chronic lymphocytic leukemia (CLL). Kappa Bence Jones proteinuria and the glomerular deposition of kappa-light chain were observed. Although treatment with cyclophosphamide and prednisolone tended to reduce the level of proteinuria, the administration of angiotensin-converting enzyme inhibitor, enalapril, resulted in complete remission of nephrotic syndrome.
(Internal Medicine 39: 256-259, 2000)

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