Intralobar Pulmonary Sequestration Presenting Increased Serum CA19-9 and CA125

Hisanaga YAGYU; Hideki ADACHI; Kinya FURUKAWA; Hiroyuki NAKAMURA; Akihiko SUDOH; Shuuji OH-ISHI; Fumihiro TSUCHIDA; Kouji KISHI; Makoto SAITOU; Takeshi MATSUOKA

doi:10.2169/internalmedicine.41.875

Hisanaga YAGYU, Hideki ADACHI, Kinya FURUKAWA, Hiroyuki NAKAMURA, Akihiko SUDOH, Shuuji OH-ISHI, Fumihiro TSUCHIDA, Kouji KISHI, Makoto SAITOU, Takeshi MATSUOKA

Author information

Hisanaga YAGYU
The Fifth Department of Internal Medicine, Tokyo Medical University
Hideki ADACHI
The Fifth Department of Internal Medicine, Tokyo Medical University
Kinya FURUKAWA
Department of Chest Surgery, Tokyo Medical University, Kasumigaura Hospital
Hiroyuki NAKAMURA
The Fifth Department of Internal Medicine, Tokyo Medical University
Akihiko SUDOH
The Fifth Department of Internal Medicine, Tokyo Medical University
Shuuji OH-ISHI
The Fifth Department of Internal Medicine, Tokyo Medical University
Fumihiro TSUCHIDA
The Fifth Department of Internal Medicine, Tokyo Medical University
Kouji KISHI
The Fifth Department of Internal Medicine, Tokyo Medical University
Makoto SAITOU
Department of Chest Surgery, Tokyo Medical University, Kasumigaura Hospital
Takeshi MATSUOKA
The Fifth Department of Internal Medicine, Tokyo Medical University

Keywords: tumor markers, mucus, resection, course, immunohistochemical staining

JOURNAL FREE ACCESS

2002 Volume 41 Issue 10 Pages 875-878

DOI https://doi.org/10.2169/internalmedicine.41.875

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Abstract

A 39-year-old man was admitted to our hospital for further evaluation of a consolidated shadow and clarification of the cause of serum tumor marker elevation (CA19-9 496.2 U/ml, CA125 160.6 U/ml). Chest computed tomography revealed a well-defined homogeneous nodule in the left S¹⁰. Angiography showed one aberrant artery, branching from the ascending aorta. Intralobar pulmonary sequestration was diagnosed and the sequestrated lung was resected. Microscopic findings of the sequestrated lung showed a mucus-containing cystically dilated bronchus, which was covered with ciliated cylindrical epithelium. Immunohistochemical staining showed positive staining for CA19-9 and CA125 in both the ciliated cylindrical epithelium and mucus. Serum values of tumor markers returned to their normal range after surgery.
(Internal Medicine 41: 875-878, 2002)

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