Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
Lupus Retinopathy Associated with a High IFN-α Level in the Cerebrospinal Fluid
Masahiro KONDOYohko MURAKAWAYoshiko SUMITAHisashi MASUDAShotai KOBAYASHI
Author information
JOURNALS FREE ACCESS

2002 Volume 41 Issue 9 Pages 754-756

Details
Abstract

An 18-year-old woman who presented with photosensitivity, butterfly rash and acute visual disturbance was diagnosed as SLE with retinopathy. The level of IFN-α in the cerebrospinal fluid (CSF) was markedly elevated. Her visual acuity recovered with high-dose prednisolone therapy. IFN-α in the CSF also reduced to within the normal range. The mechanism causing lupus retinopathy is not clearly understood. Although the association between lupus retinopathy and a high level of IFN-α has not been reported, the injection of IFN-α is known to frequently cause retinopathy in hepatitis patients. We discuss the possibility of IFN-α causing retinopathy in SLE patients.
(Internal Medicine 41: 754-756, 2002)

Information related to the author
© The Japanese Society of Internal Medicine
Previous article
feedback
Top