Successful Treatment of Limited Disease-Small Cell Lung Cancer with Multimodality Treatment Consisting of Concurrent Chemoradiotherapy, High-Dose Chemotherapy with Autologous Peripheral Blood Stem Cell Transplantation and Surgical Resection

Katsuyuki HOTTA; Hiroshi UEOKA; Katsuyuki KIURA; Masahiro TABATA; Eisei KONDOH; Yoshihiko SEGAWA; Hiroshi DATE; Nobuyoshi SHIMIZU; Tadashi YOSHINO; Mine HARADA; Mitsune TANIMOTO

doi:10.2169/internalmedicine.42.1223

Katsuyuki HOTTA, Hiroshi UEOKA, Katsuyuki KIURA, Masahiro TABATA, Eisei KONDOH, Yoshihiko SEGAWA, Hiroshi DATE, Nobuyoshi SHIMIZU, Tadashi YOSHINO, Mine HARADA, Mitsune TANIMOTO

Author information

Katsuyuki HOTTA
The Department of Medicine II, Okayama University Medical School
Hiroshi UEOKA
The Department of Medicine II, Okayama University Medical School
Katsuyuki KIURA
The Department of Medicine II, Okayama University Medical School
Masahiro TABATA
The Department of Medicine II, Okayama University Medical School
Eisei KONDOH
The Department of Medicine II, Okayama University Medical School
Yoshihiko SEGAWA
The Department of Medicine II, Okayama University Medical School
Hiroshi DATE
The Department of Surgery II, Okayama University Medical School
Nobuyoshi SHIMIZU
The Department of Surgery II, Okayama University Medical School
Tadashi YOSHINO
The Department of Pathology II, Okayama University Medical School
Mine HARADA
The Department of Medicine I, Kyushu University Medical School
Mitsune TANIMOTO
The Department of Medicine II, Okayama University Medical School

Keywords: small cell lung cancer, chemoradiotherapy, high-dose chemotherapy, autologous peripheral blood stem cell transplantation, surgery

JOURNAL FREE ACCESS

2003 Volume 42 Issue 12 Pages 1223-1227

DOI https://doi.org/10.2169/internalmedicine.42.1223

Details

Abstract

A 65-year-old man with limited disease-small cell lung cancer was treated with concurrent chemoradiotherapy which resulted in a partial response. He further received high-dose chemotherapy with autologous peripheral blood stem cell transplantation. Development of non-small cell carcinoma was, however, suspected at a site of the residual nodule in cytological examination using bronchoscopy. He then underwent lobectomy, which revealed that the nodule was composed of necrotic tissue. He has been alive without recurrence for seven years. This multimodality treatment appeared to be effective for this patient. However, further investigation is necessary to clarify the role of multimodality treatment.
(Internal Medicine 42: 1223-1227, 2003)

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