Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
Preclinical Gushing's Syndrome Presenting with Isolated Adrenocorticotropin (ACTH) Deficiency-like Manifestations and Severe Hypoalbuminemia without Overt Adrenal Masses in a Patient with Chilaiditi Syndrome and Mental Retardation
Keiichi IKEDAMasato MIZUGUCHIToshihiro EBISAWAMasaki YOSHIDAHiroyuki UCHIDAHideaki OKABEToru SEKITAKatsuyoshi TOJONaoko TAJIMATatsuo HOSOYA
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2003 Volume 42 Issue 5 Pages 410-415

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Abstract

A 52-year-old man with Chilaiditi syndrome and mental retardation was admitted to Kanagawa Rehabilitation Hospital for severe hypoglycemic coma with malnutrition. This patient was first diagnosed as partial isolated adrenocorticotropin deficiency according to his symptoms and clinical course, but he was finally diagnosed as preclinical Cushing's syndrome. Manifestations of this case seemed unusual in spite of autonomic cortisol secretion and the detailed mechanisms of symptoms were unclear. The present case indicates that preclinical Cushing's syndrome may present with various manifestations, and careful diagnosis is necessary.
(Internal Medicine 42: 410-415, 2003)

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