Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
Primary Bilateral Adrenal Intravascular Large B-cell Lymphoma Associated with Adrenal Failure
Ayumi FUKUSHIMAYosuke OKADATakahisa TANIKAWATakashi ONAKAAya TANAKATakehiro HlGASHIJunichi TSUKADAYoshiya TANAKA
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2003 Volume 42 Issue 7 Pages 609-614

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Abstract

We report a rare case of bilateral primary adrenal non-Hodgkin's lymphoma with adrenal failure. A 66-year-old woman developed symptoms of adrenal failure. The cause of adrenal failure was suspected to be malignant lymphoma based on the high levels of serum soluble interleukin-2 receptor and LDH. Bilateral adrenalectomy was performed and pathological examination showed intravascular large B-cell lymphoma (IVL). Although complete remission was achieved, recurrence occurred three months later with brain metastases. IVL should be suspected in patients with bilateral adrenal tumors who present with rapidly progressive adrenal failure.
(Internal Medicine 42: 609-614, 2003)

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