抄録
Thee present paper deals with the observations, made on the serum cholinesterase activity in various types of pulmonary tuberculosis and the changes of activity during the comse of pulmonary tuberculosis treated with thoracoplasty or chemotherapy. The cholinesterase activity was determined manometrically by means of the Warburg instrument and estimations of the serum protein fraction were carried out on some cases, by means of the paper electrophoretic method and cupper sulfate method.
The correlation between the cholinesterase activity and the serum albumin concentration is also discussed.
Results were as follows:
1) In the cases of thoracoplasty the cholinesterase activity decreased definitely for one month after operation, and recovered gradually to the pre-operation state of activity by about 6 months.
2) In the chemotherapy group, the serum cholinesterase activity of the cases, whose clinical signs were markedly improved by chemotherapy, increased during and after the chemotherapy.
3) The level of the serum cholinesterase activity of far advanced cases was distinctly low. The discrepancy between the cholinesterase activity of the far advanced cases and that of moderately advanced or minimal cases was statistically significant.
4) In the far advanced cases, the serum albumin decrease and the serum globulin increase were found. The correlation between the serum cholinesterase activity and the albumin concentration was statistically significant.
