2011 Volume 87 Issue 6 Pages 226-239
The cause of “so-called meningitis in infancy (SCMI)” was not clarified for about 30 years in our country from the middle of the Meiji Era (1867–1912) until the end of the Taisho Era (1912–1926). Professor Ikutaro Hirai of pediatrics at Kyoto University cleared up the cause in 1923. After his first report, so many articles on SCMI were published as though the flood burst the dam. Although a few authors were against the Hirai’s lead-poisoning theory, the great majority of authors presented evidence in support of his study. In this report, we reviewed articles on SCMI published in Acta Paediatrica Japonica which were issued in the period of 1923~1926. The articles which we dealt within this sketch involved pathology, laboratory test studies and animal experiments, continuing from reviews, statistics, surveys, case-reports and clinical experiences in the first part.