Abstract
Infiltration of eosinophils io the stroma is occasionally seen in malignant tumors, and there is some relation between eosinophilic infiltration and prognosis of squamous cell carcinoma (SCC) originating in the esophagus, lung and other organs. However there are few reports of oral SCC with infiltration of eosinophils. The present paper reports a case of oral SCC with a severe degree of eosinophilic infiltration. The patient was a 71-year-old female whose chief complaint was a white lesion in her tongue. Histologic examination revealed the lesion to he well differentiated SCC with infiltration of numerous eosinophils in the stroma. A few eosinophils had infiltrated in the parenchyma. Infiltration of eosinophils was clearly demonstrated by Luna stain. Chemotherapy had effect on the lesion and surgically resected material showed complete disappearance of SCC.
