2008 Volume 22 Issue 5 Pages 765-769
A 25-year-old female with complaints of dry cough and general malaise was referred to our hospital. Chest X-ray revealed a mass shadow in the left lower lung field. A multiple cystic lesion was detected, extending from the upper mediastinum to the left lower thoracic cavity on chest CT and MRI. The left lobe of the thymus with multiple cystic lesions was resected using the VATS technique. Histopathological examination revealed that the mass was a multilocular thymic cyst which was reported by Suster, but with no neoplastic lesions. Multilocular thymic cyst-like changes are sometimes presented in association with thymic Hodgkin's disease or thymic seminoma. Malignant transformation and complication with some autoimmune diseases of thymic cyst were also reported (Sjögren's syndrome, myasthenia gravis, etc.). Thus, careful examination and evaluation for cystic lesions within the thymus are required.