Abstract
We report a rare case of pulmonary metastasis from breast cancer with an 18-year disease-free interval, together with a review of the literature. At an annual examination, a 64-year-old female who had undergone a left modified radical mastectomy for breast cancer 18 years previously exhibited an abnormal shadow on a chest radiograph. The chest CT films demonstrated a nodule of 1 cm in diameter with a well-defined and irregular margin in S1 of the right lung. The nodule was suspected to be either metastatic or primary lung cancer, and so thoracoscopic surgery was selected. The intraoperative frozen sectional diagnosis was pulmonary metastasis from breast cancer. In Japan, only 9 cases of pulmonary metastasis from breast cancer with a long disease-free interval of over 15 years have been reported in the literature. We reviewed the literature and discussed the clinical features