2012 Volume 26 Issue 2 Pages 171-174
A 75-year-old woman with a past history of breast cancer, gastric cancer, and renal cell carcinoma was found to have an abnormal shadow on chest computed tomography, and was referred to us. Chest CT revealed a nodule in right segment 8. Retrospectively, the tumor had been 3 mm in diameter three years previously and 4 mm two years previously. The tumor was surgically resected because of its gradual growth over three years, and was suspected as a metastatic pulmonary carcinoma. The intraoperative frozen section was diagnosed as metastatic carcinoma of renal cell carcinoma.
The tumor was composed of clear cells with abundant cytoplasm surrounding sinusoidal thin-walled vessels. Immunohistochemically, the tumor was positive for PAS and MelanA and negative for CD10 and HMB-45, being diagnosed postoperatively as a clear cell tumor of the lung. Clear cell tumor of the lung is rare and must be distinguished from metastatic pulmonary carcinoma of renal cell carcinoma. To our knowledge, there has been no reported patient with a past history of renal cell carcinoma. We report this case with a bibliographic review.
