2015 Volume 29 Issue 4 Pages 540-544
A 67-year-old male with a left lung tumor presented at our hospital. He was diagnosed with squamous cell carcinoma (cT2aN0M0 cStage IB). Left upper lobectomy with mediastinal lymph node dissection was performed, and the pathological findings showed poorly differentiated squamous cell carcinoma (pT2aN0M0 pStage IB). Seventy-six days after the operation, fever and left pleural effusion were recognized on outpatient follow-up. Surgery was indicated because of suspected empyema. However, pleural dissemination was found, and no pathogenic bacteria were detected within the specimen. His serum G-CSF level was elevated before the second operation, but had not been elevated before the first operation. Immunohistochemical staining with an anti-G-CSF monoclonal antibody showed positive results in the tumor from the second, but not the first, operation. Based on these findings, we diagnosed the patient with a G-CSF-producing lung cancer showing recurrence after complete resection.
