2015 Volume 29 Issue 5 Pages 587-592
Liposarcoma in the mediastinum or chest wall is rare. We report a case of liposarcomas in both regions with different histologies. A 67-year-old man was referred to our hospital because of an abnormal shadow on a chest radiograph. CT showed a 55-mm mass in the mediastinum, and a 47-mm mass in the right anterior chest wall. We suspected myxoid liposarcoma and lipoma, respectively. Thoracotomy was performed for the mediastinal mass. It was diagnosed as myxoid liposarcoma histologically, and the surgical margin was microscopically positive. He received adjuvant radiotherapy to the mediastinum with a total dose of 60 Gy in order to prevent tumor recurrence. During the follow-up after radiotherapy, the mass in the chest wall had been growing slowly. Sixteen months after the thoracotomy, the chest wall tumor was marginally resected, and diagnosed as well-differentiated liposarcoma. Since myxoid and well-differentiated types have different genetic alterations, we concluded that these tumors had developed independently. He was alive without any evidence of recurrence as of 19 months after the chest wall operation.
