A surgical case of synchronous multiple lung cancer with infrequent histopathological features in a single lobe

Abstract

A 68-year-old male was referred to our hospital due to an abnormal shadow on a radiograph in his medical checkup. Chest CT showed multiple masses in the right upper lobe, one of which was revealed to be squamous cell carcinoma by bronchoscopic biopsy. Right upper lobectomy with lymph node dissection was performed with video-assisted thoracic surgery. Pathological examination revealed adenosquamous carcinoma (pT3c (pl3) N1 M0 -IIIA) and large cell neuroendocrine carcinoma (pT3 (pm1) N0 M0 -IIB). Post-operative radiation therapy up to 58 Gy was performed for the chest wall invasion. No recurrence had been observed as of one year and 10 months after the surgery. Here, we report a rare surgical case of synchronous multiple lung cancer with various histopathologic features in a single lobe.