2017 Volume 31 Issue 7 Pages 890-895
A 68-year-old woman was radiologically followed after left upper lobectomy for lung adenocarcinoma. Her chest CT showed a ground glass nodule (GGN) in the right middle lobe that increased in size and density in the central region during follow-up. Laboratory examination before surgery showed high gamma-globulin. She underwent VATS middle lobectomy 5 years after lung cancer surgery. Pathological findings demonstrated the infiltration of plasma cells and lymphocytes to the lung interstitium, and she was diagnosed with plasma-cell type Castleman's disease based on the polyclonality of in situ hybridization. Multicentric Castleman's disease should be considered for patients with GGN and high gamma-globulin.
