The Journal of the Japanese Association for Chest Surgery
Online ISSN : 1881-4158
Print ISSN : 0919-0945
ISSN-L : 0919-0945
Neoadjuvant chemoradiotherapy followed by tracheal resection and reconstruction in patient with primary tracheal squamous cell carcinoma
Mariko TakemuraChihiro TakasakiMasashi KobayashiHironori IshibashiEmiko SugawaraKenichi Okubo
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2020 Volume 34 Issue 1 Pages 24-29

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Abstract

The diagnosis of tracheal carcinoma is likely delayed due to the lack of early symptoms, and complete tumor resection rates remain low. We report a tracheal carcinoma patient who underwent neoadjuvant chemoradiotherapy followed by tracheal resection and reconstruction. A 47-year-old man with hemosputum was diagnosed with primary tracheal squamous cell carcinoma. The tumor was 6 cm long (nine cartilaginous rings), and esophageal invasion and metastasis to the right para-tracheal lymph node were suspected. He received chemotherapy consisting of Cisplatin-Vinorelbine with concurrent radiotherapy (50-Gy in 25 fractions). Although staging after the induction therapy revealed partial regression of the tumor and lymph node, re-biopsy of transtracheal mucosa indicated residual malignant cells. To achieve local control, we performed tracheal resection and reconstruction with an omentoplasty at anastomosis. He was discharged without any problems with anastomosis and has remained free from recurrence for 13 months. There is a risk associated with chemoradiotherapy followed by tracheal resection and reconstruction, but it can be safe and effective with careful case selection and surgery.

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© 2020 The Japanese Association for Chest Surgery
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