2020 Volume 34 Issue 1 Pages 67-71
Paragangliomas typically arise from the paraganglionic system, and are rarely observed in the middle mediastinum. Here, we report the case of a patient with a paraganglioma located in the middle mediastinum. A 46-year-old woman was found to have an abnormal mass on chest computed tomography (CT). The mass displayed a contrast effect in the middle mediastinum. From the findings on chest CT and magnetic resonance imaging (MRI), we suspected the mass to be a paraganglioma and performed iodine-123-labeled meta-iodobenzylguanidine (123I-MIBG) scintigraphy, which revealed high accumulation in the mass. Therefore, the middle mediastinal tumor was resected by median sternotomy. The tumor was surrounded by the superior vena cava, ascending aorta, and right pulmonary artery. The tumor also had many blood vessels flowing from the aortic arch and coronary arteries, and these vessels were ligated at the time of tumor resection. The histological diagnosis of the lesion was paraganglioma. The patient has been doing well and was free from recurrence 18 months after surgery. Although a paraganglioma in the middle mediastinum is rare, it can be readily diagnosed by accurate preoperative examination.