2001 Volume 15 Issue 2 Pages 131-135
A case of well differentiated fetal adenocarcinoma in a 27-year-old female is reported. An abnormal mass shadow was pointed out on chest roentgenogram. Six months later, due to an increase in the left upper lobe mass shadow, she was admitted to our hospital. She underwent left upper lobectomy with mediastinal lymph node dissection on December 11, 1999. The operative findings showed that an elastic hard tumor, 26×16mm in size, was localized in S3 and S4 of the left lung. Histopathologically, the case had complex glandular structures resembling fetal lung and morules, but there were no sarcomatous features. The stroma was scant and was composed of benign spindled cells.
ChromograninA and neuron-specific enolase were present in a few glandular epithelial cells and in morules. Therefore, we diagnosed the tumor as well differentiated fetal adenocarcinoma. There are also some discrepancies in the clinical course and prognosis of the tumor. It is suggested that it is necessary to collect as many cases as possible, to make definite classifications and examine the clinical course and prognosis of pulmonary blastoma.
