2002 Volume 16 Issue 6 Pages 704-707
We encountered a case of lung cancer associated with myelodysplastic syndrome (MDS). A 65-year-old man was admitted in November 1999 because of abnormal shadow on chest X-ray. He was diagnosed as having MDS 4 months before admission. Chest CT scan demonstrated a rapid growth of the tumor in right S1, which strongly suggested primary lung cancer. Laboratory studies on admission revealed: white blood cell count 2, 510/mm3 with 24.5% neutrophils, hemoglobin 9.2g/dl, and platelet count 8.1×104/mm3. Supportive therapy including administration of granulocyte colony-stimulating factor and transfusion of red blood cells and platelets was performed during perioperative period. Intraoperative aspiration needle biopsy of the tumor demonstrated squamous cell carcinoma. Right upper lobectomy and mediastinal node dissection were carried out safely. There were no postoperative complications, such as infection or bleeding. We discuss the surgical indications and perioperative management of a lung cancer patient with MDS.