2004 Volume 18 Issue 5 Pages 606-611
Microwave Coagulation Therapy (MCT) is increasingly used in cases of malignant liver tumors . MCT has been expected to be applied to lung cancers, yet it has never really been examined for its influence on normal lung tissues. With a purpose of investigating its clinical applicability to pulmonary diseases, we performed MCT on the normal lung tissues of a dog, in the power conditions of 20, 40, and 60W and with the treatment times of 15, 30, and 60 seconds in each power condition. We investigated the diameter of the maximum coagulation area and histopathological changes in normal tissue by H-E stain, immediately after and one week after the coagulation treatment. Coagulation area expanded with the increase of the power of output and the coagulation time . More than 10mm coagulation area was obtained under 40W-60sec or 60W-30sec coagulation. A maximum 23mm coagulation was obtained under the condition of 60W-60sec coagulation, but over-coagulation caused necrotic cavitations.
In conclusion, we have demonstrated in the present sutdy that optimum condition to obtain security more than 10mm coagulation area is 40W-60sec or 60W-30sec coagulation.
