1992 Volume 6 Issue 5 Pages 609-614
Primary malignant fibrous histiocytoma (MFH) of the lung is very rare. As far as we know, only 15 cases have been reported in the literature in Japan. A 74-year-old female was admitted because of bloody sputum. Her chest X-ray showed a round tumor shadow (40×37 mm) in the left lung field. Since the tumor increased size, left upper lobectomy was performed. The specimens showed the typical storiform pattern of fibroblast-like cells and histiocyte-like cells with scattered giant cells. The serum ferritin level was slightly increased and the serum α1-antitrypsin level was within the normal range. No abnormal finding was detected by Gascintigraphy after the operation. Therefore the tumor was diagnosed as the primary MFH of the lung. The increased serum ferritin level might be a marker for MFH.
