Impact of Perioperative Clinicopathological Factor on Serious Complication of Emergency Operations in Patients with Ulcerative Colitis

Abstract

[Purpose] The rate of serious postoperative complications following emergency or semi-emergency surgery for ulcerative colitis (UC) are higher than in the case of elective surgery. We evaluated the impact of perioperative clinicopathological factors on serious complications associated with emergency operations in patients with ulcerative colitis. [Patients and Methods] Twenty-eight patients who underwent emergency or semi-emergency surgery for UC were identified from 249 patients at the age 16 or over who underwent colectomy in our hospital. A serious complication was defined as high-grade (from IIIa on up) on the Clavien-Dindo classification. [Result] Postoperative serious complications occurred in 9 (32.1%) patients. Preoperative pulse and respiratory rates were significantly higher (107±19 vs. 84±13/min; p=0.018, 20.6±5.6 vs. 16.1±3.2/min; p=0.023) and serum Ch-E was significantly lower (65±33 vs. 111±55 IU/L, p=0.013) in patients who had undergone emergency or semi-emergency surgery compared with elective surgery. There was no significant relationship between other perioperative clinicopathological factors and serious postoperative complications of emergency or semi-emergency surgery. [Conclusion] The patient's nutritional and general status may impact on development of serious complications after emergency or semi-emergency surgery for patients with UC.