We investigated caregiving conditions and the relationship between caregivers and impaired elderly people as predictors of caregivers' burnout. Participants were 783 family members caring for elderly people aged 65 and over, who had elderly care insurance. A questionnaire surveyed the demographic characteristics, and the physical and mental conditions of elderly people; as well as caregiving conditions, social support, and burnout. Results indicated that caregiving conditions were different in different generations. Social support and caregivers' burnout varied as a function of gender. The analysis of predictors suggests that positive and negative aspects of social support must be considered in order to fully understand caregivers' burnout.