2016 年 14 巻 1 号 p. 59-64
High-frequency electromagnetic wave stimulation induces proliferation and differentiation of osteoblasts. The aim of the study is to histopathologically evaluate the effects of high-frequency electromagnetic waves on bone formation.
Bone defects with a diameter of 4.8 mm were created on the left and right sides of the calvarias of Wistar rats. The active electrode was placed in the left defect and high-frequency electromagnetic stimulus was applied for 1 s and repeated five times. This was performed twice a week for 2 weeks. The right defects were not stimulated (control group). After 8 weeks, histological specimens were prepared by hematoxylin and eosin (HE) staining, and the rate of bone formation was measured.
The rate of bone formation was significantly larger in the experimental group than in the control group. These results indicate that high-frequency electromagnetic wave stimulation enhances bone formation in rat calvarial defects.