Abstract
The purpose of this study is to clarify the relation between the pathological changes and clinical factors. As the former, myocardial fibrosis, coronary stenosis, diameter of aortic root, pathological changes of aortic root and heart weight were taken, and as the latter, aging, blood pressure, diabetes mellitus, serum cholesterol and ECG were taken.
The subjects were 100 autopsied cases including 62 males and 38 females aged 18-93 years without congenital heart disease, valvular disease, cardiomyopathy, myocarditis and myocardial infarction.
Each pathological and clinical items was classified into two or three categories and then analyzed by multi-variate-statistical analysis.
As the results of this study, the obvious correlation were observed in following three groups:
1) severe myocardial fibrosis and hypertension.
2) increased heart weight, moderate myocardial fibrosis, diabetes mellitus and LVH in ECG.
3) severe coronary stenosis and hypercholesterolemia.
