Lower Intake of Vitamin B₂ and Calcium by Japanese Females in Mitochondrial Haplogroup D

抄録

Single-nucleotide polymorphisms (SNPs) of the β₃-adrenergic receptor (BAR-3) and mitochondrial NADH dehydrogenase subunit-2 (ND2) genes are well established to be associated with obesity or other lifestyle-related diseases. We previously reported that the BAR-3 normal (Trp64Trp) + ND2 variant (Mt5178A) group preferred much more carbohydrate and less animal protein than the other genetic groups. In the present study, cross-sectional analysis of these genotypes was conducted with a much greater number of participants. The BAR-3 normal (Trp64Trp) + ND2 variant (Mt5178A) group was confirmed to have the significantly higher carbohydrate energy ratio and lower animal protein intake than the others. The statistical significance was greater than that obtained previously. In addition, an association of low intake of vitamin B₂ intake and calcium with this genetic group was newly found in this expanded study.