Effect of Mazindol on Monosodium Glutamate-Induced Obesity in Rats

Shunichi MURANO; Yasuko SHIKI; Yoko FUJIYAMA; Yoh ISHIKAWA; Toshio NISHIDE; Kohji SHIRAI; Masako OTABE; Norihiro SASAKI; Nobuo MATSUOKA; Yasushi SAITO; Sho YOSHIDA

doi:10.3164/jcbn.2.33

Shunichi MURANO, Yasuko SHIKI, Yoko FUJIYAMA, Yoh ISHIKAWA, Toshio NISHIDE, Kohji SHIRAI, Masako OTABE, Norihiro SASAKI, Nobuo MATSUOKA, Yasushi SAITO, Sho YOSHIDA

著者情報

Shunichi MURANO
The Second Department of Internal Medicine, School of Medicine, Chiba University
Yasuko SHIKI
The Second Department of Internal Medicine, School of Medicine, Chiba University
Yoko FUJIYAMA
The Second Department of Internal Medicine, School of Medicine, Chiba University
Yoh ISHIKAWA
The Second Department of Internal Medicine, School of Medicine, Chiba University
Toshio NISHIDE
The Second Department of Internal Medicine, School of Medicine, Chiba University
Kohji SHIRAI
The Second Department of Internal Medicine, School of Medicine, Chiba University
Masako OTABE
Kawasaki Seitetsu Chiba Hospital
Norihiro SASAKI
Kawasaki Seitetsu Chiba Hospital
Nobuo MATSUOKA
Kawasaki Seitetsu Chiba Hospital
Yasushi SAITO
The Second Department of Internal Medicine, School of Medicine, Chiba University
Sho YOSHIDA
The Second Department of Internal Medicine, School of Medicine, Chiba University

キーワード: monosodium glutamate-induced obesity, mazindol, acyl-CoA synthetase, triglyceride synthesizing activities, anorexic action

ジャーナルフリー

1987 年 2 巻 1 号 p. 33-39

DOI https://doi.org/10.3164/jcbn.2.33

詳細

抄録

Mazindol decreased food intake and the body weight of rats with monosodium glutamate (MSG)-induced obesity as well as of control rats. The drug suppressed acyl-CoA synthetase and triglyceride synthesizing activities in epididymal adipose tissue of the obese rats but not of the control ones.

責任著者(Corresponding author)

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