Journal of Clinical Biochemistry and Nutrition
Online ISSN : 1880-5086
Print ISSN : 0912-0009
ISSN-L : 0912-0009
In Vivo Effect of L-Cysteine on Ethanol-Induced Alterations in Membrane-Bound ATPases of Liver and Kidney of Experimental Rats
Natarajan CHANDRAMOHANAbdul Shukkur EBRAHIMEllappan BABUDhanapal SAKTHISEKARAN
著者情報
キーワード: ethanol, ATPase, L-cysteine, glutathione
ジャーナル フリー

1996 年 20 巻 3 号 p. 225-230

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Decreased activities of Na+, K+-ATPase in liver and kidney, Mg2+-ATPase in kidney, and Ca2+-ATPase in liver were observed in alcoholic rats (3.0g of ethanol/kg body weight, 30% [v/v]) given twice daily for 30 days compared with those of the controls. Increased activities of Ca2+-ATPase in kidney and Mg2+-ATPase in liver were also observed in the alcoholic rats. All the above metabolic alterations induced by alcohol were effectively avoided by L-cysteine (20mg/100g body weight) given twice daily for 30 days.

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